rFAB Ethyl Glucuronide (EtG) HEIA

With this homogeneous enzyme immunoassay for the detection of the alcohol metabolite Ethyl Glucuronide (EtG) in urine, Immunalysis and Specialty Diagnostix introduce the new recombinant fragment antigen-binding technology. This novel assay configuration provides enhanced performance, superior specificity and targeted selectivity.

Assay Characteristics

  • 97% or greater accuracy leading to fewer unconfirmed positives
  • More flexibility through dual cut-off – 500 ng/mL and 1,000 ng/mL
  • Liquid, ready-to-use reagents, calibrators and controls – no reconstitution required
  • Application protocols for all major clinical chemistry analysers
  • Packaging tailored for your laboratory’s specific needs
Specialty Diagnostix rFAB EtG Assay

Background

Ethyl Glucuronide (EtG) is a direct ethanol metabolite. It is formed in the liver by enzymatic conjugation of ethanol with glucuronic acid. The presence of EtG in urine is positive proof that the person tested has recently been in contact with alcohol. EtG is produced whenever an individual has been exposed to products containing ethyl alcohol that get into the bloodstream. However, tests for EtG cannot determine the source of ethanol.

While alcohol is only detectable for a few hours after actual consumption, testing for EtG offers a considerably wider window of detection. As a biomarker, EtG can be used to test for ethanol consumption and to monitor alcohol abstinence. Possible applications include alcohol withdrawal programmes, patients in need of liver transplantations, detection of potential alcohol abuse, pregnant women, drivers hoping to renew their licenses or prisoners on parole.